Archive for 2012
What system does Parkinson’s disease affect?
I know it affects the autonomic central nervous system. But more specifically, does it affect the sympathetic or parasympathetic system?
While Parkinson’s seems to begin as a disease of the central nervous system, it actually affects most of the systems in the body.
Because Parkinson’s is a chronic progressive neurodegenerative disease, it can eventually work its way through all systems: digestive (gastrointestinal), respiratory and circulatory systems, musculoskeletal. excretory and urinary systems, reproductive system, immune system, endocrine system.
The autonomic nervous system controls heart rate, digestion, respiration rate, salivation, perspiration, diameter of the pupils, the discharge of urine, and sexual arousal. Although most of its actions are involuntary, some ANS functions work together with the conscious mind, in breathing for example. Common symptoms of a problem are erectile dysfunction, dizziness, decrease in blood pressure and urinary incontinence; all of which are common to PD.
Since your question is also specific to the parasympathetic nervous system, read the abstract below (link also provided) and then you can find your own words. The important thing to know is that not all PD patients develop Lewy bodies. But the dementia caused by their presence is found in both Parkinson’s disease with dementia (PDD) and in Lewy Body Disorder (LBD) with parkinsonian symptoms. A third condition associated with lewy bodies is ANS.
“Lewy body formation has been considered to be a marker for neuronal degeneration, because postmortem studies of Parkinson’s disease (PD) patients have shown loss of neurons in the predilection sites for Lewy bodies. We systemically studied the autonomic nervous system in patients with PD. Lewy bodies were widely distributed in the hypothalamus, sympathetic system (intermediolateral nucleus of the thoracic cord and sympathetic ganglia) and parasympathetic system (dorsal vagal and sacral parasympathetic nuclei). The number of neurons in the intermediolateral nucleus was significantly reduced. Furthermore, Lewy bodies were also found in the enteric nervous system of the alimentary tract, cardiac plexus, pelvic plexus and adrenal medulla. These findings indicate that both central and peripheral autonomic nervous systems are involved in the disease process in PD.”
Another relation comes with orthostatic hypotension and the sudden drop in blood pressure upon standing. This can become common in PD because it is a side effect of aging and in one sense, PD is very accelerated aging of select neurons which result in the many symptoms of aging.
You can read about the imbalance between the autonomic and the parasympathetic nervous system
in ANS disorder: “Malfunction of the ANS is called autonomic failure. It results from an imbalance between the sympathetic and parasympathetic divisions. Aging is associated with several abnormalities in ANS function that can impair elderly people’s adaptation to stress.
The most common signs of ANS impairment are a drop in blood pressure when a person is standing or stands up suddenly (orthostatic hypotension) or a drop in blood pressure within one hour of eating a meal (postprandial hypotension).
The drop in blood pressure causes inadequate blood flow to the brain. That’s why it’s common for people with this problem to feel dizzy or lightheaded. These conditions occur more often in people with high blood pressure.
Several abnormalities make normal elderly people more likely to have low blood pressure. The onset of disease in old age, such as diabetes, stroke and Parkinson’s disease, as well as medications used to treat them, may have other adverse effects in the ANS that are obvious in the cardiovascular system.”
You might also be interested in reading about the clinical trial which is currently enrolling by invitation only in Finland.
Duodenal Levodopa Infusion, Quality of Life and Autonomic Nervous System in Parkinson’s Disease
“Parkinson’s disease (PD) is one of the most common neurodegenerative Disorders with increasing prevalence because of aging population. The main symptoms include rigidity, hypokinesia, tremor and impaired balance, but the disease also causes autonomic dysfunction. Motor fluctuations are common treatment related problems in PD, around 50-70% of patients treated with levodopa finally develop motor fluctuations. Continuous duodenal levodopa infusion has been effective in the treatment of motor dysfunction in advanced PD. However, little is known of its effects on autonomic nervous system”
This is another area in general research and there is not the body of information to help answer everything.
Parkinson’s disease – The Neurodegenerative Diseases Initiative (HD) | A film by the Wellcome Trust
My husband has been off work for 8 months,he has been for Incapacity Benefit assessment and been sighned off for 1 year. I need sites that can give me some ideas on how to try and help him and me, I am finding the stress of dealing with him and all the finacial issues is wareing me down. Thanks if you know what I an talking about and can help.
I have Ptsd for which I am receiving counselling and medication.
Try the link below these people deal specifically with trauma. They have a helpline which you can call during the day and they will be more than happy to talk to you and give you advice and help.
It is very difficult coping with the effects is has on both of you and I hope you get the help you need.
West Ridge Academy Suggests How To Help Your Teen Overcome Destructive Eating Habits
West Ridge Academy says that having an Eating Disorder is bad enough but it can be even more terrifying when your child has it. Not all eating Disorders are immediately life threatening but they all should be taken very seriously. Many qualified and professional facilities like West Ridge Academy are out there and experts recommend you utilize professional help when faced with a child with an Eating Disorder. Addressing an eating disorder right away is one of the best and most effective ways in solving the problem. There are people out there that can help your child overcome it.
Why Eating Disorders Occur
Eating Disorders typically begin with a changing image of self by focusing self worth on our own physical appearance rather that who we are. Because the inner and outer persons are very different. The personality and/or the spirit is the most beautiful part of a person. Teen are particularly susceptible to the poisons of the media teaching them that physical appearance defines them. The primary driver of most societies is this obsession with the physical body. No one is perfect and seeing these images makes people want and expect to be perfect which is impossible. West Ridge Academy can help those suffering from Eating Disorders. The root cause of eating disorders are diverse and ofter stem from some physiological issue, thus another reason you should seek professional treatment. It’s not entirely understood why they occur.
While many teenagers live perfectly normal lives and have a healthy body image, for others they take this to extreme and end up with an eating disorder because they have become so obsessed with their weight and how they look to other people that they start to hate food or use it in a negative way. Binging followed by a purge is know as bulimia and simply not eating to control weight and size is called Anorexia. Either Way West Ridge Academy is a good resource. Parents need to watch their children closely if their child acts peculiarly towards food or you notice any new behavior patterns develop in your child. For example a child may skip food often or say they ate someplace else to avoid eating a family meal. This can be an early warning sign that something is wrong.
How Parents Can Help
Becoming a positive role model for your child can be a very effective way to teach them about healthy body image and nutrition. When all you can do isn’t enough to save your child from the grasp of an eating disorder professional facilities like West Ridge Academy are there to help. Often once the eating disorder has taken root it is very difficult to overcome without professional help. Eating disorders are always life threatening however they are much more dangerous to teens as they are missing out on the nutrition they need during this important developmental stage of there life that without the proper nutrition they will suffer life long effects.
A parent should call professionally organizations like West Ridge Academy because these conditions can lead to:
• Drop in pulse, breathing rate, or blood pressure
• Fingernail breaks, or hair loss
• Loss of a period for a woman
• Lack of concentration
• Anemia can develop
• Joints become swollen
• Brittle bones
• Pain in the stomach
• Stomach or kidney damage
• Tooth decay from stomach acids
• Expansion of salivary glands from throwing up
• Low Potassium, can lead to heart problems
Parents don’t have to suffer and watch their child go through an eating disorder.
Professionals like those at West Ridge Academy can help your child get back on track and on the road to recovery by teaching them health eating habits and healthy self image. Contact a professional right away if there is a problem whether someone at West Ridge Academy or not.
Special thanks to the Mormon Tabernacle Choir for being the special guests at West Ridge Academy’s Eating Disorder awareness night.