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Blood Disorders

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blood disorders
Does prolong use of quinine sulfate cause blood Disorders? Used over 15 years?

Platelette count ranges from 43,000 to 67,000. Avg. of 50,000
Need back surgery. Physcians will not do surgery.
Could quinine sulfate cause spleen to enlarge? Possible ITP.

Well, I don’t know the answers to all those questions, but I know that Quinine is used for malaria attacks and my brother used it whenever he had an attack for years. I understand that there is now a cure for malaria (not sure, I only heard it once).
I don’t know what your condition is, or how your platelet count would relate to needing back surgery. If your doctor(s) won’t do it, I assume that they have determined that you don’t need it or it is contraindicated by your other condition(s).
Do you maybe just have some vertebrae out of place and need a Chiropractic adjustment? Have you had X-Rays or any tests to determine what your back problem is? I assume that if you have a kidney infection, the doctors would have found it.
Here is something I found on platelet count. This makes it sound as if yours is extremely low, unless you left out a zero. If it is truly that low compared to the normal range shown below, that sounds as if you may have a problem with your immune system.

Normal results. The normal range for a platelet count is 150000-450000 platelets per microliter of blood. Abnormal results. An abnormally low platelet level …
www.healthatoz.com/…/common/standard/transform.jsp?requestURI=/healthatoz/Atoz/ency/platelet_count.jsp

For the enlarged spleen, here is what the Mayo Clinic shows:
www.mayoclinic.com/health/enlarged-spleen/DS00871

Here is a site for the quinine sulfate usage. It sounds as if you have been taking it continuously for 15 years.

www.edruginfo.com/dud_quininesulfate.htm

Blood Vessel Disorders (Part 1)

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Clotting Disorders

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clotting disorders
Dobermans and clotting Disorders?

A lot of people jump on other breeds for problems, but this one really bugs me. Why is it that there are still Dobermans with Von Willebrands? There is testing for this disorder, and it is well known if you breed 2 affected dogs together then you will have an entire litter of affected pups, and if you breed 1 parent that is affected and 1 that is not, then you will get an entire litter of pups that are carriers. So, why is it that breeders in this breed have not bred this out of the Doberman?
Well Fluffy do you want a gold star for that stupid answer?? Duh, yes it does, my question is with Dobes!!!

You can spot the “affecteds” but you can’t spot the carriers. The gene could be carried for generations and not show up, until you breed a carrier to carrier and get an affected.

Some breeds (like Scotties) now have a DNA test for this, but Dobermans do not yet. The gene fault is different in different breeds.

Basset hounds don’t have a DNA test for vWD, but we do now (just in the past year) have a test for Basset Hound Thrombopathia, which is another serious Bleeding Disorder. They’ve also uncovered the marker for a similar disease in Great Pyrenees and European Landseers (NOT the Landseer version of the Newfoundland but a separate breed).

Even with the tests, it will still take time to eliminate the disease completely. Since BHT is estimated to be carried by 25% of the Basset Hound population, to automatically eliminate all carriers from breeding would exclude many excellent dogs who have much to contribute to the breed. The researchers who located the gene recommend that such a carrier should simply be bred to a clear dog only, and all puppies in the resulting litter must be tested and the best prospects selected from the clear ones.

EDIT: I stand corrected regarding the vWD test for dobes.

Thrombophilia / Clotting Disorders

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